Could this be three in a row for Lady Antebellum? They dethroned Rascal Flatts in 2010 and hope to keep the trophy into 2013. The trio have certainly had the hits, and their concert ticket sales have grown tremendously. More than that, perhaps, is that they're a crossover act that brings new fans to the genre. ACM voters love that.

They will win if: They don't lose votes to the Band Perry and Rascal Flatts. Sonically, these three are similar -- at least more similar than the other two -- and if their votes get split up, that could leave the door wide open for Zac Brown Band.